Valuing Life

Each Softgel capsule contains –
Ferrous Ascorbate – 100 mg
Folic Acid – 1.5 mg
Zinc – 22.5 mg
Methylcobalamin -1500 mcg
In India, nearly 70% of women are estimated to be iron deficient. Iron deficiency anaemia (Haemoglobin, Hb < 12gm/dl) is one of India’s major public health problems particularly in women. Effective control of iron deficiency anaemia decreases the incidence of fatigue, body ache, headache, lack of concentration and menstrual complications.
IDA(iron deficiency anemia) is a consequence of decreased iron intake, increased iron loss from the body or increased iron requirements. Blood loss during menstruation can predispose women to have poor iron stores and the presence of excess menstrual bleeding can contribute to the development of IDA in women.IDA can cause menorrhagia*, which in turn can aggravate IDA. With severe anemia, there may be amenorrhoea* as well.
It usually takes about 6-10 weeks for Hb to return to normal after initiation of oral iron therapy.
Ferrous Ascorbate – (Ferrous ascorbate 100 mg = 14 mg of Elemental Iron)
IRINA MAX contains ferrous ascorbate which is considered as Gold standard in Iron therapy due to its properties. It is a synthetic molecule of iron and ascorbic acid. This has fantastic absorption as ascorbic acid increases the absorption of Iron. The ferrous form is absorbed thrice as much as the ferric form of iron. There is no dissociation of ferrous ascorbate on entering the gastrointestinal (GI) tract due to the stable chelate of iron with ascorbate. So there is no action of food inhibitors as the complex does not dissociate. Ascorbate is reducing agent and prevents oxidation.
Ascorbic acid reduces ferric iron to ferrous iron, which remains soluble even at neutral pH, and enhances the absorption of iron. It also inhibits the conversion of ferrous to ferric iron; this maintains the iron in highly soluble ferrous form, leads to increased absorption of iron and reduces the amount of free radicals generated, thereby minimizing adverse GI effects.
Ascorbic acid has been shown to inhibit the effect of phytates, phosphates and oxalates on iron absorption by the formation of soluble iron ascorbate complexes and by inhibiting the formation of insoluble iron complexes.
Studies shown that Ferrous ascorbate leads to speedy Hb rise (2.5 to 3 gm%) within 30 days. Ferrous ascorbate higher absorption leads to less GI disturbances and no interaction with food and can be given at any time.
Folic Acid –
Folic acid also known as vit.B9, which is itself not biologically active, but its biological importance, is due to tetrahydrofolate and other derivatives after its conversion from dihydrofolic acid in the liver. Folic acid and Folate (the form naturally occurring in the body) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in biological reactions involving folate. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy. Children and adults both require folic acid to produce healthy red blood cells and prevent anemia.
The Folate-B12 Connection
Folic acid, vitamin B12 and iron all undergo complicated interactions inside the body. Having an insufficient amount of any one of these nutrients may prevent the others from doing their jobs properly.
For example, the formation of healthy red blood cells requires both folate and B12. This is one of the reasons that supplements for vitamin B12 so often contain folic acid as well. It just ensures that the two vitamins are in balance and can work together properly.
The second reason to supplement both vitamins is that having too much folate can mask the symptoms of B12 deficiency, and vice versa. This masking effect can severely delay a diagnosis of either B12 or folate deficiency, with potentially serious consequences.
Methylcobalamin –
Methylcobalamin is a form of Vitamin B12, a vitamin that has strong effects on the brain and nervous system while also being important for cell growth and reproduction. Adequate intake of the B12 is especially important for pregnant women, as a severe deficiency can have disastrous consequences on the developing nervous system of a fetus, yet be difficult to detect.
In the body, methylcobalamin is used in a variety of processes, including: the production of red and white blood cells, the regeneration of RNA and DNA, the conversion of fats, carbohydrates, and protein to energy, the synthesizing of proteins and fats, nerve cell and sheath maintenance, methylations (a type of chemical reaction affecting DNA expression), brain function maintenance, choline synthesis, maintenance of epithelial and mucous membrane cells, maintenance of normal bone marrow, and maintenance of a normal gastrointestinal tract.
A building block of life Zinc, a mineral present in many foods, plays an essential role in the construction of your baby’s cells and DNA during pregnancy. It is needed for cell division and tissue growth, supporting normal development as your baby grows. It has been suggested that maternal zinc deficiency may compromise infant development and lead to poor birth outcomes. It also prevents Pre-term births. Zinc aids in greater Infant Birth weights & Head circumferences
1. Iron deficiency Anaemia
2. Pregnancy and Lactation
3. Post surgical convalescence
4. Chronic blood loss e.g. angiodysplasia*, gynecological disturbances, hemorrhoids, stomach or small intestine ulcers
5. Worm infestation
6. Menorrhagia*
IRINA MAX may interact with barbiturates, diphenylhydantoin, primidone, tetracycline group of drugs, quinolones, penicillamine, L-dopa, methyldopa, bisphosphonates and calcium salts.
IRINA MAX is contraindicated in patients with iron supplements allergy, patients with hemosiderosis*, haemolytic anemia*, active infections and hemochromatosis*.

Oral iron preparations may aggravate existing peptic ulcer, regional enteritis and ulcerative colitis. Iron compounds taken orally can impair the absorption of tetracycline antibiotics. Antacids given concomitantly with iron compounds decrease iron absorption.
 Small size Softgel capsule
 Very easy to swallow for patients having nausea & vomiting
 No metallic taste
 Better absorption
 Higher Bioavailability
 Complete dose of Methylcobalamin added
 Complete combination for treating Anaemia
Glossary –
Menorrhagia – abnormal heavy bleeding at menstruation.
Amenorrhoea – abnormal absence of menstruation
Angiodysplasia – In gastroenterology, angiodysplasia is a small vascular malformation of the gut. It is a common cause of otherwise unexplained gastrointestinal bleeding and anemia.
Hemochromatosis – an iron disorder in which the body simply loads too much iron. This action is genetic and the excess iron, if left untreated, can damage joints organs, and eventually be fatal.
Hemosiderosis – a form of iron overload disorder resulting in the accumulation of hemosiderin.
Hemolytic anemia – is a condition in which red blood cells are destroyed and removed from the bloodstream before their normal lifespan is over.